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1 In silico analysis of the impact of R152H mutation on GPX4 (GPX4 U46C PDB: 2OBI) structure

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FIGURE 3 Another notable finding revealed by PET and NMR (nuclear magnetic resonance) spectroscopy analysis, is that in the brains of patients affected by ASD were found decreased glucose utilization and reduced ATP levels, further confirming mitochondrial dysfunction (Palmieri and Persico, 2010)